Sphingosine-1-phosphate相关论文
Spinster homolog 2(SPNS2)is the only membrane transporter that has been demonstrated to secrete sphingosine-1-phosphate(......
Sphingosine-1-phosphate ameliorates left ventricular remodeling and dysfunction after myocardial inf
Background: Sphingosine-1-phosphate(S1P)/S1P receptor 1 signaling has received attention for its potential to ameliorate......
Macrophage recruitment to sites of inflammation is an essential step in host defense.However, the signals regulating the......
The sphingosine-1-phosphate/RhoA/Rho associated kinases/myosin light chain pathway in detrusor of fe
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一磷酸鞘氨醇(S1P)是一种具有生物活性的磷脂信使,在体内主要由血小板和肥大细胞分泌,其对细胞的生长、增殖以及迁移等具有重要作......
目的观察支气管哮喘发作期不同严重程度哮喘患者血中1-磷酸鞘氨醇（S1P）水平的变化，探讨S1P对哮喘患者病情严重程度的评估价值。方法采......
目的 观察S1PR2对不同时间点小鼠后肢缺血模型血流恢复情况的影响,探讨其在后肢缺血模型血管新生和血流恢复中的作用.方法 采用戊......
Blockage of sphingosine-1-phosphate receptor 2 attenuates 2,4-dinitrochlorobenzene-induced atopic de
Sphingosine-1-phosphate (S1P) and its receptors have been implicated in functions of Langerhans cells and atopic dermati......
目的:探讨1-磷酸鞘氨醇(S1P)缺氧前、后处理对心肌细胞缺氧/复氧(H/R)损伤拮抗作用的差异及相关机制.方法:分离SD乳鼠(1～2d龄)心肌......
,Pharmacokinetics of H002, a novel S1PR1 modulator, and its metabolites in rat blood using liquid ch
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目的研究1-磷酸鞘氨醇受体2(S1PR2)对小鼠血管通透性的作用。方法将野生鼠和S1pr2-/-鼠(S1PR2基因缺乏)气管内滴注脂多糖(LPS)制备......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
背景1-磷酸鞘氨醇(sphingosine-1 -phosphate，S1P)是鞘脂的代谢产物，不仅与细胞表面特定受体(S1PR1-5)结合产生多种生物学效应，还作为......
自然杀伤性T细胞(NKT)和树突状细胞(DC)等免疫细胞作为免疫系统的重要组成成份在维持机体内环境的稳态和免疫功能的正常发挥中起着......
Accumulated evidences have demonstrated that signal transducer and activator of transcription 3(STAT3)is a critical link......
目的探讨蛋白激酶C在1-磷酸鞘氨醇（Sphingosine 1-phosphate，S1P）激活大鼠心肌细胞核转录因子（Nuclear transcription factor，NF）-κB信......
神经酰胺和鞘胺醇-1-磷酸是具有生物活性的鞘磷脂,它们不仅是构成细胞膜的重要组分,也可以作为第二信使在细胞信号转导中发挥重要......
目的探讨血清1-磷酸鞘氨醇(S1P)及铁代谢水平与腹膜透析(PD)患者发生腹膜炎的相关性。方法选择2016年8月至2019年8月在我院长期维......
目的探讨S1P/S1P1信号通路在糖尿病心肌病大鼠心肌损伤中的作用与机制。方法40只SD大鼠分为正常对照组和2型糖尿病心肌病，每组各20......
目的观察成人支气管哮喘（简称哮喘）急性发作时血清1-磷酸鞘氨醇（S1P）水平变化，探讨其在哮喘发病中的临床意义。方法选择2015年11月至201......
目的：探究1-磷酸鞘氨醇（S1P）对缺氧／复氧乳鼠心肌细胞的保护作用及其分子机制。方法：在大鼠乳鼠心肌细胞原代培养基础上，应用液体石蜡覆......
目的：探讨血浆脂蛋白上鞘氨醇-1-磷酸（S1P）和磷脂转运蛋白（PLTP）的相互作用及机制。方法：检测雄性10周龄PLTP转基因（PLTP-Tg）及野生型（WT）小......
目的研究阿托伐他汀对1-磷酸鞘氨醇（S1P）诱导乳鼠心肌细胞肥大反应中的作用。方法原代培养乳鼠心肌细胞,测定心肌细胞体积和[3H]-亮......
目的：观察1－磷酸鞘氨醇（ S1P）对人脐静脉内皮细胞（ HUVEC）增殖和迁移的影响，探讨其作用机制。方法将HUVEC分为A～F组，A组只加细胞培养液，B～F组......
目的 探讨病毒性脑炎及化脓性脑膜炎患儿脑脊液（CSF）1-磷酸鞘氨醇（S1P）的变化.方法 选取病毒性脑炎患儿30例,化脓性脑膜炎患儿30例以及......
1-磷酸鞘氨醇(S1P)是一种有活性的脂质分子,作用广泛,在多种疾病中发挥作用,如肿瘤、心血管疾病、骨代谢、糖尿病等。研究报道,S1P......
Regulatory role of sphingosine kinase and sphingosine-1-phosphate receptor signaling in progenitor/s
Balanced sphingolipid signaling is important for the maintenance of homeostasis.Sphingolipids were demonstrated to funct......
The sphingosine kinases, SK1 and SK2, produce the potent signaling lipid sphingosine-1-phosphate (S1P). These enzymes ha......
Sphingosine-1-phosphate (S1P) is a blood-borne lipid mediator with pleiotropic biological activities. S1P acts via the s......
目的建立生物样品中磷酸鞘氨醇（S1P）的定量方法。方法采用有机溶剂萃取、碱性磷酸酶脱磷酸、衍生化后经高效液相色谱仪测定动物血清......
目的:研究1-磷酸鞘氨醇(S1P)对心室肌细胞膜钙离子通道的作用及机制.方法:Langendorff离体心脏逆向灌流法分离豚鼠心室肌细胞,随机......
Expressions of Sphingosine-1-phosphate (S1P) Receptors, Sphingosine Kinases in Malignant Bone and So
Sphingolipids are ubiquitous components of cell membranes. Their metabolites ceramide, sphingosine, and sphingosine-1-ph......
目的探讨凋亡抑制因子1-磷酸-神经鞘氨醇（S1P）对环磷酰胺（CTX）联合顺铂（DDP）诱导的S180荷瘤小鼠卵巢功能损害的干预作用及其对肿瘤化疗效......
The sphingolipid metabolites ceramide,sphingosine,and sphingosine-1-phosphate(S1P) and its enzyme sphingosine kinase(Sph......
The predictive value of serum S1P and STIM1 levels after PCI for in-stent restenosis and their corre
Objective:To study the predictive value of serum S1P and STIM1 levels after percutaneous coronary intervention (PCI) for......
Blood vessels either form de novo through the process of vasculogenesis or through angiogenesis that involves the sprout......
